Colorectal (Bowel) Cancer

The Leeds Centre has had an international impact on the care of colorectal cancer (CRC) patients through world-leading research. Leeds researchers and clinicians established the effectiveness of laparoscopic surgery for CRC, and facilitated its wider use with patients. We contributed to an international reduction in deaths from recurrence of rectal cancer, with improved surgical techniques.

CRC is the third most common cancer in the UK. In most people, the exact cause is unknown. More than 85 out of 100 cases of CRC (85%) are diagnosed in people aged 60 or over. Some people have a strong family history of the disease, which means having several relatives on the same side of your family diagnosed with CRC, or one or more relatives diagnosed at a young age. About 1 in 20 cases of CRC are caused by inherited conditions*.

Our experts include the Surgeon Professor David Jayne, the Pathologist Professor Philip Quirke, the Medical Oncologist Professor Matthew Seymour, the Clinical Oncologist Professor David Sebag-Montefiore, the Cancer Epidemiologist Prof Eva Morris, the Engineer Professor Anne Neville and the Epidemiologist Professor Tim Bishop.

Our team holds many national appointments, for example Professor Jayne is the Clinical Director of the National Institute for Health Research’s Healthcare Technology Co-operative for Colorectal Therapies and Professor Quirke chairs the pathology committee of the NHS Bowel Cancer Screening Programme.

Our current research includes:

  • Translating new surgical techniques (robotic, laparoscopic) into clinical practice.
  • Reducing recurrence of disease through improved surgical techniques.
  • Discovering biomarkers (biological measures that indicate the presence/severity of a disease or how likely it is to respond to a particular treatment).
  • Analysing data on early mortality.
  • Undertaking chemoprevention (using drugs to prevent disease) trials of high-risk patients including those with a genetic predisposition.

For further information about CRC research in Leeds, please get in touch.

Source: Cancer Research UK. Cancer Research UK provides information for patients with colorectal cancer.

Page last updated: 03/10/2016